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Author: lrnlab

New article published in Cerebral Cortex: Motor control and pain processing in midcingulate cortex

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Misra and Coombes Human neuroimaging and virus-tracing studies in monkey predict that motor control and pain processes should overlap in anterior midcingulate cortex (aMCC), but there is currently no direct evidence that this is the case. We used a novel functional magnetic resonance imaging paradigm to examine brain activity while subjects performed a motor control […]

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Dana Foundation Highlights Biomarkers for Parkinson’s Disease

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Work from our laboratory was highlighted by the Dana Foundation Read more about the article by Carl Sherman: https://www.dana.org/news/features/detail.aspx?id=44642

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Review describes evidence for dopamine overdose hypothesis

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Movement Disorders Dopamine overdose hypothesis: Evidence and clinical implications. Vaillancourt DE, Schonfeld D, Kwak Y, Bohnen NI, Seidler R. About a half a century has passed since dopamine was identified as a neurotransmitter, and it has been several decades since it was established that people with Parkinson’s disease receive motor symptom relief from oral levodopa. […]

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New article shows that acute exercise reduces pain perception

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Effects of a Force Production Task and a Working Memory Task on Pain Perception Tiffany A. Paris, Gaurav Misra, Derek B. Archer, Stephen A. Coombes The goal in the current study was to examine the analgesic effects of a pinch grip-force production task and a working memory task when pain-eliciting thermal stimulation was delivered simultaneously […]

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Review: Diffusion MRI, DTI, and Movement Disorders

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Curr Neurol Neurosci Rep. 2013 Nov;13(11):400. doi: 10.1007/s11910-013-0400-1. The evolving role of diffusion magnetic resonance imaging in movement disorders. Hess CW, Ofori E, Akbar U, Okun MS, Vaillancourt DE. Abstract Significant advances have allowed diffusion magnetic resonance imaging (MRI) to evolve into a powerful tool in the field of movement disorders that can be used […]

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REM sleep problems linked with freezing of gait in Parkinson’s disease

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Neurology. 2013 Aug 14. [Epub ahead of print] Increased REM sleep without atonia in Parkinson disease with freezing of gait. Videnovic A, Marlin C, Alibiglou L, Planetta PJ, Vaillancourt DE, Mackinnon CD. OBJECTIVE: The objective of this cross-sectional study was to test the hypothesis that patients with Parkinson disease (PD) and freezing of gait (PD+FOG) […]

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New article published on Parkinson’s disease, atypical parkinsonism, and essential tremor

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Mov Disord. 2013 May 14. doi: 10.1002/mds.25491. [Epub ahead of print] Diffusion tensor imaging of Parkinson’s disease, atypical parkinsonism, and essential tremor. Prodoehl J, Li H, Planetta PJ, Goetz CG, Shannon KM, Tangonan R, Comella CL, Simuni T, Zhou XJ, Leurgans S, Corcos DM, Vaillancourt DE. Diffusion tensor imaging could be useful in characterizing movement […]

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UF study finds brain-imaging technique can help diagnose movement disorders

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http://news.ufl.edu/2013/06/13/brain-imaging/ GAINESVILLE, Fla. — A new University of Florida study suggests a promising brain-imaging technique has the potential to improve diagnoses for the millions of people with movement disorders such as Parkinson’s disease. Utilizing the diffusion tensor imaging technique, as it is known, could allow clinicians to assess people earlier, leading to improved treatment interventions […]

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People with Parkinson’s with Tremors Show Different Brain Activity Than Those Without Tremors

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Science News: People with Parkinson’s with Tremors Show Different Brain Activity Than Those Without Tremors People with Parkinson’s disease (PD) who experience tremor of the hand or leg show different brain activity than people without tremors, according to a report in the January 2013 issue of the Journal of the American Medical Association Neurology. These […]

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Exercise & Parkinson’s disease paper accepted in Movement Disorders

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Mov Disord. 2013 Mar 27. doi: 10.1002/mds.25380. [Epub ahead of print] A two-year randomized controlled trial of progressive resistance exercise for Parkinson’s disease. Corcos DM, Robichaud JA, David FJ, Leurgans SE, Vaillancourt DE, Poon C, Rafferty MR, Kohrt WM, Comella CL. The effects of progressive resistance exercise (PRE) on the motor signs of Parkinson’s disease […]

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