Author Archives: lrnlab

New article in PAIN – Functional Imaging in Chronic Pain

Link to site Functional brain activity during motor control and pain processing in chronic jaw pain Roy, Arnaba; Wang, Wei-en; Ho, Rachel L.M.; Ribeiro-Dasilva, Margarete C.; Fillingim, Roger B; Coombes, Stephen A. Changes in brain function in chronic pain have … Continue reading

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Biomarkers in Parkinson’s – Science Trans Med

Biomarkers Perspective Published in Science Translational Medicine http://stm.sciencemag.org/content/10/454/eaam6003    

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Beta Band EEG Relates to Putamen fMRI in Parkinson

Download Paper Abstract We investigated the effect of acute levodopa administration on movement-related cortical oscillations and movement velocity in Parkinson’s disease (PD). Patients with PD on and off medication and age- and sex-matched healthy controls performed a ballistic upper limb … Continue reading

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Recruiting PhD Students 2018

We are actively recruiting PhD students for the Fall 2018 semester. We use a range of systems neuroscience techniques that include functional magnetic resonance imaging (fMRI), structural MRI, diffusion imaging (DTI), electromyography (EMG), high-density electroencephalography (EEG), and pain stimulation procedures. … Continue reading

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NIH Press Release

Press Release Here

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Validated Progression Marker of Parkinson’s Disease

Article here Abstract Progression markers of Parkinson’s disease are crucial for successful therapeutic development. Recently, a diffusion magnetic resonance imaging analysis technique using a bitensor model was introduced allowing the estimation of the fractional volume of free water within a … Continue reading

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Functional Imaging Predicts Dystonia Symptoms

Abstract Burciu et al. (2017) https://www.ncbi.nlm.nih.gov/pubmed/28594097 Cervical dystonia (CD) is the most common type of focal dystonia, causing abnormal movements of the neck and head. In this study, we used noninvasive imaging to investigate the motor system of patients with … Continue reading

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A Template and Probabilistic Atlas of the Human Sensorimotor Tracts using Diffusion MRI.

Cereb Cortex. 2017 Mar 14:1-15. doi: 10.1093/cercor/bhx066. [Epub ahead of print] A Template and Probabilistic Atlas of the Human Sensorimotor Tracts using Diffusion MRI. Archer DB, Vaillancourt DE, Coombes SA. Abstract The purpose of this study was to develop a … Continue reading

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Automated classification of pain perception using HD-EEG

J Neurophysiol. 2016 Nov 30:jn.00650.2016. doi: 10.1152/jn.00650.2016. [Epub ahead of print] Automated Classification of Pain Perception using High Density Electroencephalography Data. Misra G, Wang WE, Archer DB, Roy A, Coombes SA1. Translating brief millisecond-long pain-eliciting stimuli to the subjective perception … Continue reading

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Beta Oscillations Linked to Accuracy of Movement

Abstract Accurate motor performance may depend on the scaling of distinct oscillatory activity within the motor cortex and effective neural communication between the motor cortex and other brain areas. Oscillatory activity within the beta-band (13-30Hz) has been suggested to provide … Continue reading

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